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LSD (lysergic acid diethylamide) produces effects for 8 to 12 hours, but traces linger far less than cannabis or opioids. Understanding detection windows helps with drug tests, health planning, and harm reduction. This guide covers metabolism, test types, and real-world clearance times based on science and user data.
After ingestion, LSD absorbs quickly through the stomach or mouth (blotters). Peak blood levels occur in 1 to 3 hours. The liver breaks LSD into inactive metabolites like 2-oxo-3-hydroxy-LSD (O-H-LSD). Half-life ranges from 3 to 5 hours, meaning 50 percent clears every 3 to 5 hours. Full elimination takes 5 to 6 half-lives, or about 15 to 30 hours for most people.
Excretion happens mainly through urine (70 to 80 percent) and small amounts in feces. LSD itself appears in tiny amounts; tests target metabolites.
Most common for LSD screening. Detects O-H-LSD metabolite. Single dose (100 to 200 µg) clears in 24 to 48 hours. Heavy or repeated use extends up to 3 to 5 days. Standard cutoff is 0.5 ng/mL. Standard 5-panel or 10-panel workplace tests do not include LSD. Only specialized panels check.
Rare outside medical or research settings. Detects LSD directly. Window lasts 6 to 12 hours after use. Peak occurs 1 to 3 hours post-dose. Cutoff ranges from 0.1 to 0.5 ng/mL. Used in DUI cases or clinical studies, not routine employment.
Very rare and expensive. Can detect LSD use months back. Window reaches up to 90 days (grows ~1 cm/month). Limitation requires 50 to 100 strands. Cutoff is 0.1 pg/mg. Not standard. Only high-security or forensic cases use.
Almost never used for LSD. Window lasts 1 to 6 hours. Detection is possible but unreliable. No commercial kits target LSD in saliva.
From 0 to 30 minutes, absorption begins (sublingual or swallowed). Between 1 to 3 hours, peak blood concentration occurs. From 6 to 12 hours, effects fade and LSD drops below 1 ng/mL. At 24 hours, it falls below urine detection for most. At 48 hours, it clears for single use in 95 percent of people. After 72+ hours, possible trace remains in chronic users.
Workplace drug test (5-panel) remains safe after 48 hours. Probation or court-ordered tests become risky within 72 hours for moderate dose. Research studies may use ultra-sensitive LC-MS detecting up to 5 days. Hair tests, though rare, require avoidance for 90 days if concerned.
People claim LSD stays in your spine forever, but it fully metabolizes in days. Many believe vitamin C or niacin flushes it, yet no evidence supports this. Hydration helps slightly. Some think you fail a test a week later, but this stays extremely unlikely after single use.
Hydrate with 2 to 3 liters water daily. Exercise lightly to boost metabolism. Eat acidic foods like cranberries or vitamin C to support urine pH. Avoid detox drinks because most are scams for LSD. Rely on time as the only reliable method.
Microdosing (10 to 20 µg) clears between doses (every 3 to 4 days). Festival multi-day use requires 5 to 7 days. Therapy settings in clinics rarely test post-session.
A standard LSD dose clears the body within 48 hours for urine detection in most people. Blood and saliva windows close much faster, and hair tests are rare. Standard drug screens skip LSD entirely. Plan with intention, know your context, and prioritize integration over paranoia.
At Shrooms and Edibles, we sell lab-tested LSD blotters and microdose tabs for controlled, safe use. Explore our collection today.